PROGNOSTIC SIGNIFICANCE OF LYMPHOBLAST MORPHOLOGY IN ACUTE LYMPHOBLASTIC LEUKAEMIA (ALL) IN CHILDHOOD
نویسندگان
چکیده
منابع مشابه
Prognostic significance of leukopenia in childhood acute lymphoblastic leukemia
Chemotherapy-induced leukopenia has been shown to be associated with the outcomes of several types of cancer, but the association with childhood acute lymphoblastic leukemia (ALL) remains unknown. To elucidate the association of chemotherapy-induced leukopenia with the clinical outcome of childhood ALL, retrospective analysis was performed on 19 child patients with ALL treated according to the ...
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Background: Aberrant expression of cross-lineage antigens gives valuable insight into the diagnosis and prognosis of acute leukemia. In countries like India, cytogenetic tests are widely accessible. Exploring the prognostic value of an accessible test is of great importance. Therefore, establishing a population-specific immunophenotype database will enable to design an antibody panel equipped t...
متن کاملVariable detection of myeloid antigens in childhood acute lymphoblastic leukaemia.
AIMS To determine whether the use of different sources of anti-CD13 and anti-CD33 monoclonal antibodies leads to discrepant results in childhood acute lymphoblastic leukaemia (ALL), which might contribute to the wide variation in the reported incidence of myeloid antigen expressing ALL in childhood. METHODS Stored leukaemic cells from 10 children with previously defined myeloid positive ALL w...
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A prospective study of bone marrow fibrosis was made in a group of 40 children with acute lymphoblastic leukaemia to see whether it affected the prognosis or course of the disease. Secondary myelofibrosis (SMF) was present at diagnosis in 57% of the cases. It was not statistically significantly related to the prognosis or course of the disease. Thus, although trephine biopsy occasionally provid...
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OBJECTIVE To investigate the association of human parvovirus B19 infection with the onset of acute lymphoblastic leukaemia and its effect on TEL-AML-1 fusion gene and the presence of mutant P53. METHODS The case-control study was conducted at Basrah Hospital for Paediatrics and Gynaecology, Basrah, Iraq, from May 2009 to April 2010. A total of 100 blood samples were collected from 40 newly di...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 1980
ISSN: 0007-1048,1365-2141
DOI: 10.1111/j.1365-2141.1980.tb03825.x